Search on: ISGF3 TRANSCRIPTION FACTOR 
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Descriptor English:   Interferon-Stimulated Gene Factor 3 
Descriptor Spanish:   Factor 3 de Genes Estimulados por el Interferón 
Descriptor Portuguese:   Fator Gênico 3 Estimulado por Interferon 
Synonyms English:   ISGF3 Factor
Transcription Factor ISGF3
IFN Stimulated Gene Factor 3 Complex
ISGF3, Transcription Factor
Interferon Stimulated Gene Factor 3
Transcription Factor, ISGF3
IFN-Stimulated Gene Factor 3 Complex
ISGF3 Transcription Factor  
Tree Number:   D12.644.360.024.303
D12.776.157.057.061
D12.776.260.513
D12.776.476.024.386
D12.776.930.354
Definition English:   A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES. 
History Note English:   2006(1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50769 
Unique Identifier:   D050832 

Occurrence in VHL:
 

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